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Duocarmycin TM

CAS No. 157922-77-5

Duocarmycin TM( —— )

Catalog No. M26182 CAS No. 157922-77-5

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Duocarmycin TM
  • Note
    Research use only, not for human use.
  • Brief Description
    Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
  • Description
    Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
  • In Vitro
    Duocarmycin TM (60 μM; 4 d; BJAB and WSU-DLCL2 cells) is a cytotoxic agent that inhibits the proliferation of tumor cells.Cell Viability Assay Cell Line:BJAB and WSU-DLCL2 cells Concentration:60 μM Incubation Time:4 days Result:Inhibited the proliferation of tumor cells with IC50 values of 0.153 μM and 0.079μM for BJAB and WSU-DLCL2 cells, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    157922-77-5
  • Formula Weight
    466.92
  • Molecular Formula
    C25H23ClN2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 50 mg/mL (107.09 mM)
  • SMILES
    COc1cc2cc([nH]c2c(OC)c1OC)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Uddin MJ, et al. Synthesis of 5- and 6-carboxy-X-rhodamines. Org Lett. 2008 Nov 6;10(21):4799-801.
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